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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Novel context-specific genome-scale modelling explores the potential of triacylglycerol production by Chlamydomonas reinhardtii

Fig. 3

Consistency of simulated proteomes to transcriptomics, and estimated rate constants by OVERLAY. Best-fitted proteome versus measured transcriptomes at t = 4 h before (a) and after (b) the enzymatic rate constant adjustment by nonconvex QP. \(R^{2*}\) is computed using log-transformed data for simulated proteomes and measured transcriptomes, whereas \(R^2\) is computed without log-transforming. Outliers are denoted in yellow (\(\ge 3\) times) and red (\(\ge 10\) times). \(R^2\) values are computed using all points, including outliers. c Demonstrates \(K_\text {eff}\) values before calibration using OVERLAY (pre-NCQP) and after calibration (post-NCQP). Here, \(K_\text {eff} = r\cdot K_\text {eff}^\text {avg}\)

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