Fig. 2

PC-FBA simulation results of autotrophic, mixotrophic, and heterotrophic C. reinhardtii growth mode. The optimal metabolic fluxes are shown in a, where autotrophic, mixotrophic, and heterotrophic fluxes are denoted by green, blue, and red numbers, respectively. All fluxes are shown in mmol/gDW/h. A negative flux value means the flux is flowing in the opposite direction of the arrow. The dotted lines show the electron flux. All metabolites are shown in BiGG ID. Complex/enzyme abbreviations in thylakoid: PSII, photosystem II; PQ, plastoquinone/plastoquinol; Cyt b6f, cytochrome b6f complex; PC, plastocyanin; PSI, photosystem I; Fd, ferredoxin; FNR, ferredoxin NADP+ reductase; and ATPSh, CF0F1 ATP synthase. The optimal proteome of three growth modes is shown by proteome maps of b, c, and d. Each small polytope is a single protein, and its area denotes the relative abundance. Likely coloured polytope is classified under the same subsystem, which is written in white text. Only modelled proteins are drawn. *Some reactions of the TCA cycle are outside of mitochondria