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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Engineering of a newly isolated Bacillus tequilensis BL01 for poly-γ-glutamic acid production from citric acid

Fig. 1

Metabolic pathways and metabolic engineering strategies to improve the production of γ-PGA in B. tequilensis BL01. Red arrows indicate genes that are overexpressed for γ-PGA production: pyruvate dehydrogenase (pdhABCD), pyruvate kinase (pyk), pyruvate carboxylase (pycA), citrate synthase II (citZ), isocitrate dehydrogenase (icd), glutamate synthase (gltA), poly-gamma-glutamate synthase complex (pgsBCAE); Purple arrows indicate genes that are deleted: acetolactate synthase (alsS), glutamate dehydrogenase (rocG), cryptic glutamate dehydrogenase (gudB), glutamate 5-kinase (proB), 2-oxoglutarate dehydrogenase E1 component (sucA), gamma-DL-glutamyl hydrolase (pgdS), membrane-bound gamma-glutamyltranspeptidase (ggt)

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Microbial Cell Factories

ISSN: 1475-2859

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