Skip to main content
Fig. 4 | Microbial Cell Factories

Fig. 4

From: Enhancement of acarbose production by genetic engineering and fed-batch fermentation strategy in Actinoplanes sp. SIPI12-34

Fig. 4

Attenuation of glycogen synthesis and enhancement of glycogen degradation. a Overview illustration of the metabolic pathways involved in the two precursors in the synthesis of acarbose. The red arrow down represents the weakened glycogen synthesis pathway, and the green arrow up represents the enhanced glycogen degradation pathway. b Determination of glycogen content in SIPI12-34 and ΔGS/glgP during the fermentation process. c Acarbose production profiles of SIPI12-34 and ΔGS/glgP were analyzed by HPLC. Error bars show standard deviations, ***P < 0.001, **P < 0.01

Back to article page

Microbial Cell Factories

ISSN: 1475-2859

Contact us