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Table 3 Organic acid distribution for bioreactor cultivations based on the sampling points summarized in Table 2

From: Optimization of l-malic acid production from acetate with Aspergillus oryzae DSM 1863 using a pH-coupled feeding strategy

Fermentation No.

Organic acid distribution [%]a

Malate

Succinate

Fumarate

Pyruvate

α-Ketoglutarate

Oxalate

Citrate

I

47.0 ± 1.7

39.7 ± 2.4

5.3 ± 0.3

3.4 ± 0.7

0.3 ± 0.0

3.3 ± 0.1

1.1 ± 0.2

II

47.4 ± 0.6

40.7 ± 0.1

5.4 ± 0.1

2.3 ± 0.5

0.3 ± 0.0

3.0 ± 0.1

0.9 ± 0.0

III

51.7 ± 0.8

42.1 ± 0.5

3.8 ± 0.1

1.2 ± 0.2

0.2 ± 0.0

0.1 ± 0.0

1.0 ± 0.0

IV

51.0 ± 0.3

42.5 ± 0.4

4.2 ± 0.4

1.3 ± 0.0

0.1 ± 0.0

0.6 ± 0.2

0.3 ± 0.2

V

51.6 ± 0.6

42.0 ± 0.5

4.3 ± 0.0

1.5 ± 0.1

0.0 ± 0.0

0.6 ± 0.1

0.0 ± 0.0

VI

54.5 ± 0.1

40.2 ± 0.2

3.3 ± 0.2

0.6 ± 0.1

0.2 ± 0.0

0.9 ± 0.2

0.5 ± 0.1

VII

50.2 ± 2.7

43.1 ± 2.8

2.9 ± 0.2

1.6 ± 0.1

0.2 ± 0.0

0.8 ± 0.6

1.1 ± 0.1

  1. aValues were calculated as the percentage of the total acid concentration as given in Table 2