High-yield production of protopanaxadiol from sugarcane molasses by metabolically engineered Saccharomyces cerevisiae

Table 3 PPD and DM-II production of strain BY-V in 5-L bioreactor

Time (h)	PPD^a (mg/g DCW)	PPD (g/L)	[PPD/(sugar + ethanol)] (mg/g)	DM-II (g/L)	DM-II/PPD (%)
48	78.55 ± 0.36^b	1.71 ± 0.20	12.10 ± 0.32	0.07 ± 0.01	2.08 ± 0.21
72	81.86 ± 0.77	3.71 ± 0.07	14.38 ± 0.45	0.13 ± 0.04	3.35 ± 0.35
96	87.06 ± 0.45	7.16 ± 0.18	15.91 ± 0.74	0.75 ± 0.04	9.46 ± 0.43
120	100.82 ± 0.42	8.64 ± 0.13	15.16 ± 0.56	1.23 ± 0.02	12.47 ± 0.25
126	188.50 ± 0.56	15.88 ± 0.65	25.05 ± 0.47	2.19 ± 0.04	13.02 ± 0.36

^aPPD yields represented the total amounts of intracellular and extracellular extraction
^bAll data are presented as mean ± standard deviation of biological triplicates

ISSN: 1475-2859