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Table 1 Olivetolic acid production using different microbial hosts

From: Scale-up of an amoeba-based process for the production of the cannabinoid precursor olivetolic acid

Organism

PS

PO

TEE

Scalability

OA production

References

E. coli

+

+

–

+

80 mg/L

Tan, 2018 [10]

S. cerevisiae

 + 

–

 + 

+

0.48 mg/L

Gagne, 2012 [12]

S. cerevisiae

–

 + 

 + 

+

1.5 mg/L

Luo, 2019 [9]

A. nidulans

–

–

+

+/–

80 mg/L

Okorafor, 2021 [13]

D. discoideum

–

–

+

+

4.5 µg/L

Reimer, 2022 [6]

  1. PS: precursor supplementation; PO: pathway optimization; TEE: tailoring enzyme expression; OA: olivetolic acid
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Microbial Cell Factories

ISSN: 1475-2859

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