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Fig. 12 | Microbial Cell Factories

Fig. 12

From: Oral or intranasal immunization with recombinant Lactobacillus plantarum displaying head domain of Swine Influenza A virus hemagglutinin protects mice from H1N1 virus

Fig. 12

Weight changes and percent survival in mice after challenging with swIAV H3N2 virus. Groups of immunized and unvaccinated mice intranasally challenged with swIAV H3N2 virus at 1 week after the third immunization. Average body weight changes (a, d) and survival rates (b, e) were monitored for 14 days. Values indicate the mean weight changes of all of the mice in each group after virus challenge. The lungs of each mouse group were collected for viral titers (c, f) detection at 5 day post-challenge in MDCK cells and the results were calculated by value of log10. Significant difference of vaccination with DMEM non-inactivated vaccine group was recorded (*p < 0.05, **P < 0.01, ***P < 0.001)

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