Table 3 Therapeutic peptides and their uses in cancer therapy

Lactoferricin B

Bovine

Apoptosis

[93]

SALF

Shrimp

Apoptosis

[94]

KLA repeat AMP [(KLAKLAK)2]

Synthetic

Apoptosis

[95]

Pardaxin

Fish

Apoptosis

[96]

Tat-bim

Fusion of Tat and Bim peptides

Apoptosis

[97]

Poropeptide-Bax

Bax

Apoptosis

[98]

R8-Bax

Fusion of poropeptide-Bax with argenine

Induced cell death

[98]

CT20-NP

Derived from Bax

Interruption the membrane integrity

[99]

RRM-MV

Synthetic peptide

cytotoxic to different cancerous cell lines

[100]

TIP

Derived from p53

Inhibition of p53-MDM2 interaction

[101]

PNC-27

Synthetic peptide

necrosis

[102]

Kahalalide F

Marine-derived peptide

necrosis

[103]

Polybia- MPI

Natural ACP

Induction of necrosis in various leukemia cells

[104,105,106]

ABT-510

De novo design

Inhibition of tumor angiogenesis

[107, 108]

HNP-1

Human

Inhibition of angiogenesis

[104, 109]