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Fig. 1 | Microbial Cell Factories

Fig. 1

From: GC/MS-based 13C metabolic flux analysis resolves the parallel and cyclic photomixotrophic metabolism of Synechocystis sp. PCC 6803 and selected deletion mutants including the Entner-Doudoroff and phosphoketolase pathways

Fig. 1

Carbon core metabolic network of Synechocystis 6803 for the co-utilization of glucose and CO2 under photomixotrophic conditions. The network comprises the Calvin-Bassham-Benson (CBB) cycle, the Emden-Meyerhof-Parnas (EMP) pathway (including the PGI shunt), the Entner-Doudoroff (ED) pathway (including the ED shunt), the oxidative pentose phosphate (OPP) pathway (including the OPP shunt), the phosphoketolase (PK) pathway, the TCA cycle, and anabolic routes. Abbreviations:, glucose 6-phosphate (G6P), fructose 6-phosphate (F6P), dihydroxyacetone phosphate (DHAP), glyceraldehyde 3-phosphate (GAP), 3-phosphoglycerate (3PG), phosphoenolpyruvate (PEP), pyruvate (PYR), acetyl-CoA (AcCoA), isocitrate (ICI), 2-oxoglutarate (2OG), succinate semialdehyde (SucA), succinate (SUC), fumarate (FUM), malate (MAL), oxaloacetate (OAA), 6-phosphogluconate (6PG), 2-keto-3-deoxy-6-phosphogluconate (KDPG), ribose 5-phosphate (Ri5P), ribulose 5-phosphate (Ru5P), xylose 5-phosphate (X5P), sedoheptulose 7-phosphate (S7P), erythrose 4-phosphate (E4P), extracellular carbon dioxide (CO2_EX), intracellular carbon dioxide (CO2). The reaction numbers refer to the biochemical network, used for flux estimation (Additional file 1: Table S9). Anabolic fluxes into biomass (X) are given as vx

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