Fig. 2

Overall structure of OhyEm and OhyRe. A Proteins are shown in cartoon representation. Dashed lines indicate un-modelled loop regions. Domain organization of OhyEm (PDB-ID: 4uir; [46]): Protomer I is shown in cartoon representation: Domain I in light blue, domain II in blue, domain III in deep teal and domain IV in marine. Protomer II is shown in a transparent surface representation and cartoon representation depicted in light gray. The FAD cofactor is shown as black stick representation. B Domain organization of OhyRe (PDB-ID: 5odo; [48]): Domain I in green, domain II in orange, domain III in deep teal and domain IV in red. The shown FAD cofactor is derived from the superposition with OhyEm. The FAD is depicted in black stick representation. C Superposition of protomer I of OhyEm and OhyRe in identical orientation as in panel B. One protomer of OhyEm is shown in light blue. The terminal extensions of OhyEm are clearly visible on the right site of the panel. Figures were prepared with PYMOL (Schrödinger Inc.)