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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Biosensor-driven, model-based optimization of the orthogonally expressed naringenin biosynthesis pathway

Fig. 5

A Barplots visualizing the occurrence frequency of each promoter variant (BX) at each enzymatic step in the characterized pathways (TAL, 4CL, CHS, CHI) versus the achieved naringenin titer with those pathways containing the specific promoter—enzyme combination. B Identical to A but each promoter variant occurence versus the achieved titer is plotted separately for its presence in combination with either of the two isozymes. (P_X: promoter TIF of enzymatic step X; CDS_X: enzyme variant; NA: not applicable due to failed CDS DNA sequencing; Rg: Rhodotorula glutinis; Fj: Flavobacterium johnsoniae; Pc: Petroselinum crispum; At: Arabidopsis thaliana; Ph: Petunia hybrida; Gh: Gerbera hybrida; Ms: Medicago sativa; TAL: Tyrosine ammonia-lyase; 4CL: 4-coumaroyl-CoA ligase; CHS: Chalcone synthase; CHI: Chalcone isomerase)

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Microbial Cell Factories

ISSN: 1475-2859

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