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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Engineering microbial consortia of Elizabethkingia meningoseptica and Escherichia coli strains for the biosynthesis of vitamin K2

Fig. 5

Design of Elizabethkingia meningoseptica and Escherichia coli co-culture system for vitamin K2 biosynthesis. (I) Mevalonate pathway: atoB acetoacetyl-CoA acetyltransferase; HMGS HMG-CoA synthase; HMGR HMG-CoA reductase; MK mevalonate kinase; MVD1 mevalonate pyrophosphate decarboxylase; idi IPP isomerase. MenA (1,4-dihydroxy-2-naphthoate octaprenyltransferase), MenG, and UbiE (Q-8/MK-8 biosynthesis methyltransferase) encoded the head structure biosynthesis enzymes that are involved in the vitamin K2 biosynthetic pathway starting from isochorismate. Gene names in red represent the overexpressed genes. (II) HPLC analysis of vitamin K2 products in E. meningoseptica and E. coli co-culture system

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Microbial Cell Factories

ISSN: 1475-2859

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