Table 2 Proteomic profiles of central carbon metabolism of S. cerevisiae strains BY4742, BY4742 + pLJ529-ZNF1, and the bud21∆ + pLJ529− ZNF1 during fermentation of mixed 0.05% glucose (w/v) with or without 2% xylose (w/v) at 48 h

Glycolysis/Gluconeogenesis/TCA cycle

Pfk1

6-phosphofructokinase 1 and 2

0.91–0.96

0.34–0.59

1.95–3.50

Fba1

Fructose-bisphosphate aldolase

1.04

0.86

1.69

Glk1

Glucokinase

0.89

0.51

4.85

Pgi1

Glucose-6-phosphate isomerase

1.39

1.05

1.91

Tdh1-3

Glyceraldehyde-3-phosphate dehydrogenase 1–3

0.87–0.88

0.74–1.34

1.23–1.90

Hxk1, 2

Hexokinase 1 and 2

1.04–1.29

0.20–0.29

4.01–8.02

Pgk1

Phosphoglycerate kinase

1.11

0.55

2.51

Gpm1

Phosphoglycerate mutase

0.93

1.1

1.39

Eno1, 2

Enolase 1 and 2

0.93–0.94

0.3

2.57–2.73

Pdb1

Pyruvate dehydrogenase

1.28

0.98

4.25

Pyk1

Pyruvate kinase

0.89

0.57

2.42

Tpi1

Triose-phosphate isomerase

1.28

0.72

2.02

Pdc1, 5, 6

Pyruvate decarboxylase 1, 5, and 6

0.66–0.79

0.37–0.52

1.74–3.37

Aco1

Aconitate hydratase

0.98

0.66

2.92

Cit1

Citrate synthase

0.81

0.56

3.27

Lat1

Dihydrolipoyllysine-residue acetyltransferase

0.76

0.8

3.09

Mdh1

Malate dehydrogenase

1.33

1.05

1.86

Pck1

Phosphoenolpyruvate carboxykinase

0.33

0.5

1.18

Pentose phosphate pathway and Oxidoreductase

Adh1, 2

Alcohol dehydrogenase 1 and 2

0.74–0.98

0.90–1.16

1.05–2.45

Gnd1

Phosphogluconate dehydrogenase

0.95

0.77

2.67

YDL124W

Aldo–keto reductase

0.71

0.3

3.73

Tal1

Transaldolase

0.93

0.4

2.11

Tkl1

Transketolase

1.37

0.87

2.04

Hexose transport

Hxt1-7

Hexose transporter

1.36–1.76

0.57–0.82

3.49–10.43