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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Metabolic engineering of Rhodotorula toruloides IFO0880 improves C16 and C18 fatty alcohol production from synthetic media

Fig. 4

Fatty alcohol titers produced from single mutant strains derived from 880CF and tested in glass culture tube fermentation. For genes with multiple identified homologs, the Mycocosm proteinID is provided. Error bars represent ± standard deviation of biological triplicates. Presence of an asterisk indicates statistically significant improvement compared to 880CF (p < 0.05, student t-test). ACC1 acetyl-CoA carboxylase gene, ACL1 ATP-citrate lyase gene G6PD1 R. toruloides glucose-6-phosphate dehydrogenase gene, Yl G6PD Y. lipolytica glucose-6-phosphate dehydrogenase gene, Yl ME1 gene encoding Y. lipolytica malic enzyme, DGA1 diacylglycerol acyltransferase gene, LRO1 phospholipid:DAG acyltransferase gene, ARE1 acyl-CoA:cholesterol acyltransferase gene, FAA1 fatty acyl-CoA synthase gene, TGL2 triglyceride lipase gene, FAO fatty alcohol oxidase gene, PXA1 peroxisomal ABC transporter gene, AMPD1 AMP deaminase gene, SCD1 stearoyl-CoA desaturase gene

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