Fig. 7
From: Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments
Genetic organization of the PUM gene cluster and the proposed pathway to PUM. a Genetic organization of the PUM gene cluster. The gene cluster (pum) was from Streptomyces sp. ID38640. The sap gene cluster was from Streptomyces albus DSM 40763, show high homology to pum gene cluster. b Proposed biosynthetic pathways to PUM. APU, 5′-amino pseudouridine; Glu-APU, Glutamine-APU; GAA, guanidino acetic acid. X = H or PO3H2