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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Efficient conversion of phytosterols into 4-androstene-3,17-dione and its C1,2-dehydrogenized and 9α-hydroxylated derivatives by engineered Mycobacteria

Fig. 6

Characterization of ADD- and 9OH-AD-producing mutants during phytosterol fermentation. a HPLC profile of the extracts from the phytosterol fermentation by ADD- and 9OH-AD-producing mutants for 144 h compared with those of HGMS2Δkstd211 + ΔkshA226 and the HGMS2Δkstd211 + ΔkshB122 mutants. (1) 4-AD; (2) ADD; (3) 9OH-AD and (4) BA. *: unknown HGMS2 metabolites when the strain was cultured without phytosterol. b, c Time course of ADD and 9OH-AD yields by the HGMS2kstd2 + Δkstd1+ΔkshA226 and the HGMS2kshA51 + Δkstd211+ΔkshB122 mutants, respectively

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Microbial Cell Factories

ISSN: 1475-2859

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