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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Saccharomyces cerevisiae as host for the recombinant production of polyketides and nonribosomal peptides

Fig. 4

A Biosynthesis of lovastation and generation of its semisynthetic analogue simvastatin. LovB lovastatin nonaketide synthase (LNKS), LovC enoylreductase, LovG multifunctional esterase, LovA cytochrome P450 monooxygenase, CPR cytochrome P450 reductase, LovF lovastatin diketide synthase (LDKS), LovD thioesterase-like acyltransferase, DMB-SMMP dimethylbutyryl-S-methyl mercaptopropionate. B Domain architectures of LovB, LovC and LovF. ER0 dysfunctional enoylreductase

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