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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Enforcing ATP hydrolysis enhanced anaerobic glycolysis and promoted solvent production in Clostridium acetobutylicum

Fig. 4

Metabolic flux changes in glycolysis (a), TCA cycle (b), ABE fermentation (c) and energy associated reactions (d) of strain 1731(pITF1) (red) compared to those of vector control 1731(pIMP1) (blue). Mean and s.d. of 1000 flux samples are shown as line and shading, respectively. GLCpts glucose phosphotransferase, PFK phosphofructokinase, GAPD glyceraldehyde-3-phosphate dehydrogenase, PYK pyruvate kinase, FDXNH hydrogen ferredoxin oxidoreductase, POR pyruvate ferredoxin oxidoreductase, PFL pyruvate formate lyase, CS citrate synthase, ACONT aconitase, ICDHyr isocitrate dehydrogenase, MDH malate dehydrogenase, PYC pyruvate carboxylase, SACOT succinyl-CoA:acetoacetate CoA-transferase, SUCOAS succinyl-CoA synthetase, SUCCex succinate cross-membrane transport, ACK acetate kinase, BUTK butyrate kinase, COAT1 acetate-acetoacetate CoA transferase, COAT2 butyrate-acetoacetate CoA transferase, ALCD alcohol/aldehyde dehydrogenase, ADC acetoacetate decarboxylase, ACACT acetyl-CoA C-acetyltransferase, BUTOH butanol dehydrogenase, ATPM maintenance ATP hydrolysis

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