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Table 3 The MIC (μM) values of recombinant and synthetic LG

From: Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris

 

MIC

P-value

Recombinant LG

Synthetic LG

Gram-bacteria

 E. coli ATCC 25922

1.77 ± 0.19

1.66 ± 0.25

0.62

 E. coli ATCC 078

1.22 ± 0.19

1.00 ± 0

0.15

 E. coli UB1005

1.22 ± 0.19

1.33 ± 0.25

0.62

 S. Typhimurium C 7731

1.33 ± 0.25

1.22 ± 0.19

0.62

 S. Typhimurium ATCC 14028

3.78 ± 0.44

3.56 ± 0.78

0.55

 P. aeruginosa ATCC 27853

4.44 ± 1.78

4.44 ± 1.78

1

Gram + bacteria

 S. aureus 29213

2.00 ± 0.00

1.89 ± 0.11

0.33

 S. faecalis 29212

1.89 ± 0.11

1.78 ± 0.19

0.55

 S. epidermidis ATCC 12228

1.89 ± 0.11

1.89 ± 0.11

1

 S. aureus ATCC 25923

4.44 ± 1.78

4.44 ± 1.78

1

  1. The data were derived from three independent experiments and presented as mean ± SD. P < 0.05 indicated that the MIC data of the two groups was significantly different