Table 1 The MIC (μM) values of peptides
From: Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris
| Â | MIC | ||||
|---|---|---|---|---|---|
FD | FR | (FR)2 | LG | LA | |
Gram-bacteria | |||||
 E. coli ATCC 25922 | 32.00 ± 0.00 | 7.11 ± 1.66 | 1.22 ± 0.41 | 2.22 ± 0.63 | 2.22 ± 0.63 |
 E. coli ATCC 078 | 16.00 ± 0.00 | 8.00 ± 0.00 | 1.11 ± 0.31 | 1.22 ± 0.41 | 2.44 ± 0.83 |
 E. coli UB 1005 | 16.00 ± 0.00 | 2.44 ± 0.83 | 1.00 ± 0.00 | 1.22 ± 0.41 | 1.11 ± 0.31 |
 S. Typhimurium C 7731 | 32.00 ± 0.00 | 8.00 ± 0.00 | 1.11 ± 0.31 | 1.22 ± 0.41 | 1.11 ± 0.31 |
 S. Typhimurium ATCC 14028 | 32.00 ± 0.00 | 8.00 ± 0.00 | 2.22 ± 0.63 | 4.00 ± 0.00 | 4.44 ± 1.25 |
 P. aeruginosa ATCC 27853 |  > 32 | 16.00 ± 0.00 | 2.22 ± 0.63 | 4.00 ± 0.00 | 4.44 ± 1.25 |
Gram + bacteria | |||||
 S. aureus ATCC 29213 |  > 32 | 8.00 ± 0.00 | 2.00 ± 0.00 | 2.00 ± 0.00 |  > 32 |
 S. epidermidis ATCC 12228 |  > 32 | 3.78 ± 0.63 | 2.00 ± 0.00 | 2.00 ± 0.00 |  > 32 |
 S. aureus ATCC 25923 |  > 32 | 16.00 ± 0.00 | 3.78 ± 0.63 | 3.78 ± 0.63 |  > 32 |
 S. faecalis ATCC 29212 |  > 32 | 4.00 ± 0.00 | 2.00 ± 0.00 | 2.22 ± 0.63 |  > 32 |