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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion

Fig. 6

GO term analysis for Nan and Pex expression in the mutant and parental strains. a Cellular responsive bioprocesses affected by different protein expression. Up and down represent up-regulation and down-regulation. Numbers represent the amount of genes in the up- and down-regulated terms. We compared the same terms between HA.Nan vs. LA.Nan and HA.Pex vs. LA.Pex based on up-regulation (b) or down-regulation (c). We focused on terms in part I and terms in part II that show significant differences for the expression of only one protein. The squares and dots on the plot represent the same terms. Dashed lines correspond to p-adj = 0.01. 0–2 indicates no significant differences (p-adj > 0.01) and > 2 indicates a significant difference (p-adj < 0.01). The terms A-L are marked on the plot and listed in the table (d)

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