Table 1 Representative list of therapeutic proteins produced in yeast

P. pastoris

Insulin

3 g/L Insulin precursor

[122]

S. cerevisiae

IFNα2b

15 mg/L

[142]

Y. lipolytica

IFNα2b

425 mg/L

[143]

P. pastoris

Hepatitis B antigen

7 g/L

[144]

S. cerevisiae

Glucagon like peptide 2

–

[145]

K. lactis

Human interferon β

–

[40]

P. pastoris

Human granulocyte–macrophage colony-stimulating factor

285 mg/L

[146]

P. pastoris

Human serum albumin

92.29 mg/L

[147]

H. polymorpha

HBV surface antigen

250 mg/L

[148]

H. polymorpha

Granulocyte colony stimulating factor (GCSF)

–

[26]

H. polymorpha

Rotavirus VP6 protein (RV VP6)

3350.71 mg/L

[149]

H. polymorpha

HPV type 16 L1-L2 chimeric protein (SAF)

132.10 mg/L

[25]