Table 2 Therapeutics produced from various recombinant lactic acid bacteria
From: Genetic tools for the development of recombinant lactic acid bacteria
Therapeutic products | Disorder/disease | Strains | References |
|---|---|---|---|
Interleukin-10 (IL-10) | Inflammatory bowel disease (IBD) | Lc. lactis N/S | [44] |
Interleukin-12 (IL-12) | Asthma | Lc. lactis NZ9000 | [55] |
Interleukin-6 (IL-6) | Adjuvant | Lc. lactis IL1403 | [56] |
Peanut allergen Ara2 | Hypersensitivity type I | Lc. lactis CHW9 | [57] |
Birch allergen Betv1 | Hypersensitivity type I | Lc.lactis NZ9800 | [58] |
Japanese cedar pollen allergen Cry j1 | Hypersensitivity type I | Lb. plantarum NCL21 | [59] |
HSP65-6P277 | Diabetes mellitus type I | Lc. lactis NZ9000 | [60] |
Kisspeptin | Colorectal cancer | Lc. lactis NZ9000 | [61] |
HPV-16-E7 | HPV-16 induced cancers | Lc. lactis NZ9000 | [62] |
Glycosylated tyrosinase related protein-2 | Skin cancer | Lc. lactis MG1363 | [63] |
γ-Amino butyric acid | Hypertension, anxiety | Lb. pentosus SS6 | [64] |
Hyaluronic acid | Wound healing, dermatitis | Lb. acidophilus PTCC1643 | [65] |