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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Superior production of heavy pamamycin derivatives using a bkdR deletion mutant of Streptomyces albus J1074/R2

Fig. 3

Influence of genetic and environmental perturbation on growth and pamamycin production in Streptomyces albus J1074/R2. The data show the time profiles for Streptomyces albus J1074/R2, grown on a mineral medium with 55 mM mannitol (a), and with 55 mM mannitol plus 3 mM l-valine (b), and the regulator null mutant Streptomyces albus J1074/R2 ΔbkdR, grown on a mineral medium with 55 mM mannitol plus 3 mM l-valine (c). The numbers given in the plots aside the growth data (1, 2, 3) indicate the three sampling time points for intracellular CoA ester analysis. n = 3

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