Fig. 6

PCA and muconic acid production by the TN22 strain at high pitching rate (OD₆₀₀ 16) and a high initial concentration of either glucose, xylose or a mixture of glucose and xylose. A YP medium containing 10% glucose (YPD), 10% xylose (YPX) or 6% glucose and 5% xylose (YPDX) was used, buffered with 50 mM citrate buffer at an initial pH of 5.5. B Extracellular pH, muconic acid yield and muconic acid volumetric productivity as a function of time during the fermentations shown in (A). Results are means of the three independent replicates. Error bars show standard deviation at each time point