Fig. 5
From: Bacillus subtilis revives conventional antibiotics against Staphylococcus aureus osteomyelitis
B. subtilis CFS suppresses biofilm S. aureus in a mouse model of implant-associated osteomyelitis. a Representative images of immunofluorescence staining for S. aureus. Experiments were repeated independently from 4 samples per group. Scale bar 200 μm. b Scanning electron microscopy of S. aureus on the implant surface. Experiments were repeated independently from 4 samples per group. Blue scale bar 200 μm and black scale bar 10 μm. c Representative images for hematoxylin and eosin (H&E) stained tibial sections from the osteomyelitis mice treated with PBS or B. subtilis CFS on day 14 post-infection. Scale bar 500 μm. d Histological assessment of H&E stained sections. N = 6/group, *P < 0.05 vs. control. Mann-Whitney U test