Evaluation of fecal microbiota transplantation in Parkinson's disease patients with constipation

Table 2 Outcome measures in the participants

	Before FMTa	6 weeks After FMT	12 weeks After FMT	p-value
BMI (mm/kg²)	22.01 ± 1.73	23.52 ± 1.65	24.65 ± 1.09
H-Y Grade^**	2.27 ± 0.75	1.45 ± 0.82	1.09 ± 0.83	0.0023
UPDRSII Score^**	11.36 ± 4.7	6.18 ± 3.6	4.90 ± 3.33	0.0036
NMSS^**	22.36 ± 7.05	12.55 ± 5.54	10.36 ± 4.54	0.003
PAC-QOL score^**	102.55 ± 5.05	51.27 ± 6.71	43.45 ± 5.34	< 0.0001
Wexner constipation score^*	11.63 ± 3.22	8.16 ± 2.62	6.22 ± 1.03	0.0231
HCY (μmol/L)^**	15.85 ± 2.89	12.74 ± 2.05	11.22 ± 1.85	0.002
Alb (g/L)	38.49 ± 3.92	40.38 ± 4.35	41.62 ± 4.26
UA (μmol/L)	306.13 ± 75.94	282.09 ± 65.31	274.91 ± 55.73
OCTT (min)^**	150.91 ± 12.21	NA	105.45 ± 20.18	< 0.0001

H-Y Grade: Hoehn-Yahr Grade, UPDRS II Score: Unified Parkinson’s Disease Rating Scale II Score. NMSS: non-motor symptom questionnaire, BMI: body mass index (mm/kg²), HCY: homocysteine, Alb: albumen, UA: uric acid
^* p < 0.05 Before FMTvs 12 weeks After FMT in the same patient
^** p < 0.01 Before FMTvs 12 weeks After FMT in the same patient

ISSN: 1475-2859