Fig. 1
From: Adaptive laboratory evolution accelerated glutarate production by Corynebacterium glutamicum
Schematic representation of the metabolic pathway for glutarate production, flux enforcement by deletion of gdh (left panel) and ammonium assimilation by the GS/GOGAT system (right panel). Gene names are shown next to enzyme reactions (arrows), gene deletions are indicated by red crosses. Enzymes from P. stutzeri (dark grey), E. coli (light grey) and native enzymes (orange) are highlighted. gabT, GABA/5AVA amino transferase; gabD, succinate/glutarate-semialdehyde dehydrogenase; ldcC, l-lysine decarboxylase; patA, putrescine transaminase; patD, γ-aminobutyraldehyde dehydrogenase;glnA, glutamine synthetase (GS); gltBD, l-glutamic acid-2-oxoglutarate aminotransferase (GOGAT); gdh, l-glutamic acid dehydrogenase