Fig. 3From: Immune response induced by oral administration with a Saccharomyces cerevisiae-based SARS-CoV-2 vaccine in miceCellular immune responses induced by EBY100/pYD1-RBD. a T cell proliferation. b The expression levels of IFN-γ and IL-4. c CD4+ cells mediated the secretions of IFN-γ and IL-4. d CD8+ cells mediated the secretions of IFN-γ and IL-4. The data are represented as the means ± SDs. Similar results were obtained in three independent experiments. The asterisks indicate significant differences compared with the PBS- and EBY100/pYD1-vaccinated controls. *p ˂ 0.05, **p ˂ 0.01Back to article page