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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus

Fig. 3

Codon optimization reduces the N-terminal truncation of P[4]. a Truncation variants of the original P[4] sequence by LC–MS. The N-terminus of each truncation variant is indicated on the antigen diagram and predicted RNA hairpin structure. b Relative abundance within the sample of truncated P[4] variants identified by LC–MS (top). Free energies of RNA hairpin formation after codon optimization for each variant (bottom). c SDS-PAGE of variants of P[4]

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Microbial Cell Factories

ISSN: 1475-2859

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