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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Enhanced ascomycin production in Streptomyces hygroscopicus var. ascomyceticus by employing polyhydroxybutyrate as an intracellular carbon reservoir and optimizing carbon addition

Fig. 6

Influence of carbon source addition on the cofactor concentrations, polyhydroxybutyrate content and ascomycin yield. a The effect of starch addition on the ascomycin yield of strain OphaCfkbU. b The effect of dextrin addition on the ascomycin yield of strain OphaCfkbU. c The comparison of ascomycin yield in different strains or different fermentation mediums. Medium 1 respresents the initial fermentation medium. Medium 2 respresents the fermentation medium with optimized starch addtion. Medium 3 respresents the fermentation medium with optimized dextrin addtion. Medium 4 respresents the final optimized fermentation medium. d The comparison of cofactor concentration and polyhydroxybutyrate content of strain OphaCfkbU in different fermentation medium at the end of exponential phase. The data represent the mean values of five independent biological replicates, and the error bars represent the standard deviations. Asterisks indicate the significant differences between initial medium and optimized fermentation medium. P values were calculated by two-taild Student’s t test. Single asterisk indicates P < 0.05

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