Fig. 5From: Enhanced ascomycin production in Streptomyces hygroscopicus var. ascomyceticus by employing polyhydroxybutyrate as an intracellular carbon reservoir and optimizing carbon additionEffect of polyhydroxybutyrate on by-product yield and influence of cofactors on polyhydroxybutyrate biosynthesis. a The overlapped chromatograms of ascomycin and by-product in strains FS35 and OphaCfkbU, including the structures and ratios. b The comparison of cofactor concentration and ratio between strains FS35 and OphaCfkbU at the end of exponential phase. The data represent the mean values of five independent biological replicates, and the error bars represent the standard deviations. Asterisks indicate the significant differences between initial medium and optimized fermentation medium. P values were calculated by two-taild Student’s t test. Double asterisk indicates P < 0.01. NS means the difference is not significantBack to article page