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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Expression of a recombinant FLT3 ligand and its emtansine conjugate as a therapeutic candidate against acute myeloid leukemia cells with FLT3 expression

Fig. 6

Cell viability, apoptosis and cell cycle arrest assays of MV-4-11 and THP-1 cells treated with FL-DM1. a Viability assay of THP-1 cells treated with various concentrations of drugs. FL + DM1 group: unconjugated FL and DM1 with the same concentration. b Viability assay of MV-4-11 cells treated with various concentrations of drugs. FL + DM1 group: unconjugated FL and DM1 with the same concentration. c FACS analysis of apoptosis of MV-4-11 and THP-1 cells under FL-DM1 or DM1 treatment. d Western blotting analysis of activated caspase-3 and PARP in MV-4-11 and THP-1 cells under FL-DM1 treatment. E. Cell cycle analysis of MV-4-11 and THP-1 cells treated with FL-DM1

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Microbial Cell Factories

ISSN: 1475-2859

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