Fig. 1

Time course profiles of key fermentation parameters in mutant S.nodosus ZJB2016050 and wild-type S.nodosus ZJB20140315. Four profiles were illustrated in the line chart, including the yield of AmB, dry cell weight, pH and residual glucose. The whole process could be divided into four phases, lag phase (0–24 h), exponential phase (24–108 h), stationary phase (108–132 h) and decline phase (132–168 h). Error bars show standard derivation among three experiments