Skip to main content

Table 1 Effects of MOI on lytic Staphylococcus aureus phage pSa-3 production

From: Strategy for mass production of lytic Staphylococcus aureus bacteriophage pSa-3: contribution of multiplicity of infection and response surface methodology

Bacterial inoculum (CFU/mL)

Phage inoculum (MOI)

Productionmaxa (\(\times\) 110 PFU/mL)

Production timeb (h)

2 × 108

0.01

(1.27 ± 0.057) × 10–1

7

0.0001

(4.27 ± 0.551) × 10–1

9

0.000001

(1.36 ± 0.112) × 100

24

1 × 109

0.01

(7.27 ± 1.36) × 10–1

7

0.0001

(1.68 ± 0.176) × 100

9

0.000001

(1.54 ± 0.175) × 10–2

24

0.00000001

(5.57 ± 0.17) × 10–5

24

2 × 109

0.01

(1.25 ± 0.15) × 100

9

0.0001

(3.00 ± 2.65) × 10–2

9

0.000001

(2.73 ± 0.17) × 10–4

24

0.00000001

(2.00 ± 1.00) × 10–5

24

  1. aThe phage concentration produced to the maximum. The values were shown as mean ± SD from triple replicates
  2. bTime to produce the maximum phage concentration