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Table 1 Multivariate experimental design of 11 + 3 bioreactor cultivations, nomenclature and factors with mean values over process time including standard deviation

From: Optimal process design space to ensure maximum viability and productivity in Penicillium chrysogenum pellets during fed-batch cultivations through morphological and physiological control

NameP/V [W/m3]Qs [gs/gx/h]dO2 [%]
LLL0370 ± 100.017 ± 0.0035.0 ± 1.5
HLL2012 ± 200.018 ± 0.0015.0 ± 1.6
LHL0370 ± 120.040 ± 0.0125.0 ± 3.1
HHH11900 ± 150.042 ± 0.00440.0 ± 6.5
LLH0370 ± 110.015 ± 0.00440.0 ± 5.2
MMH1535 ± 200.038 ± 0.00340.0 ± 4.1
LHH0370 ± 140.045 ± 0.00440.0 ± 5.2
HHH22700 ± 150.049 ± 0.00540.0 ± 7.5
CP11535 ± 110.034 ± 0.00522.5 ± 6.6
CP21535 ± 110.033 ± 0.00522.5 ± 5.0
CP31535 ± 120.035 ± 0.00322.5 ± 6.9
MHH1113 ± 140.054 ± 0.00540.0 ± 5.4
CP41535 ± 320.026 ± 0.00322.5 ± 3.9
HHH33000 ± 340.050 ± 0.00540.0 ± 9.5