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Fig. 7 | Microbial Cell Factories

Fig. 7

From: Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol

Fig. 7

Production of friedelin and polpunonic acid in yeast strains AM254-4 and AM254-5. a Total accumulation friedelin (white columns) and polpunonic acid (grey columns) in yeast cell cultures without the addition of cyclodextrins (pellet + media). No friedelin or polpunonic acid were found in the media. b Accumulation of friedelin and polpunonic acid in the cell pellets of cyclodextrin-treated cultures. c Friedelin and polpunonic acid content in spent media of cyclodextrins-treated cultures. d Total content (pellet and media) of friedelin and polpunonic acid in cyclodextrin-treated cultures. (n = 3, error bars correspond to standard deviation)

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