Table 2 Various recombinant probiotics secreting IL-10

L. lactis Thy12

Human IL-10

Chromosome integrated

P_thyA (constitutive)

13.7 ng/mL

[35]

L. lactis

Murine IL-10

pLB263

P_groESL (Inducible)

40.72 ng/mL

[45]

L. lactis MG1363

Murine IL-10

pT1MIL10

P1 (constitutive)

630 ng/mL

[41]

B. longum NCC2705

Human IL-10

pLR

P_hup (constitutive)

22 pg/mL

[40]

B. breve UCC2003

Human IL-10

pESH100

P_gap (constitutive)

1.9 ng/mL

[47]

B. bifidum BS42

Murine IL-10

pBEST_Exp4:IL-10

P_dnaK (constitutive)

7 ng/mL

[46]

B. bifidum BS42

Murine Il-10

pBEST_SP1181:IL-10

P_dnaK (constitutive)

24 ng/mL

[46]

B. bifidum BGN4

Human IL-10

pBESIL10

P_gap (constitutive)

1473 ng/mL

This study