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Fig. 7 | Microbial Cell Factories

Fig. 7

From: Improved production of germacrene A, a direct precursor of ß-elemene, in engineered Saccharomyces cerevisiae by expressing a cyanobacterial germacrene A synthase

Fig. 7

Production of germacrene A of yeast strains expressing AvGAS mutants carrying site-directed mutagenesis of residues Phe23, His152, and Lys268. a Sequence alignment of AvGAS with its two highly identical orthologues NsGAS and NcGAs. Phe23, His152, and Lys268 are indicated by blue triangles. b, c The effect of site-directed mutations of His152 (b), Phe23 and K268 (c) on germacrene A production-producing capability of AvGAS when expressed in yeast. Values represent the means of five biological replicates. Error bars are the standard deviations from these replicates

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Microbial Cell Factories

ISSN: 1475-2859

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