Fig. 3

Functional analysis of differential transcriptome, proteome and metabolome in pairs of EC2 vs. EC1. The KEGG enrichment analysis was carried out for the differentially expressed proteins (genes) in proteome and transcriptome (red represents up-regulation and blue represents down-regulation). The KEGG enrichment analysis was carried out for the differentially expressed profiles in proteome and metabolome. The circles and triangles represent the differential metabolites and proteins in the corresponding pathway respectively. The KEGG enrichment analysis was also carried out for the differentially expressed profiles in transcriptome and metabolome. The circles and triangles represent the differential metabolites and transcripts in the corresponding pathway respectively. “Count” is the number of genes, metabolites or proteins enriched in the pathway. “Ratio” is the ratio of the number of differential genes, metabolites or proteins to the number of genes, metabolites or proteins annotated in the pathway. The colors of circles and triangles represent the p-value of the hyper-geometric test