Fig. 1From: Expressing a cytosolic pyruvate dehydrogenase complex to increase free fatty acid production in Saccharomyces cerevisiaeSchematic representation of engineering strategies for FFA production in S. cerevisiae. G3P glyceraldehyde-3-phosphate, 3PG 3-phospho-glycerate, cPDH cytosolic pyruvate dehydrogenase. A cytosolic PDH complex was evaluated in a faa1Δ faa4Δ pox1Δ hfd1Δ mutant YJZ08 for free fatty acid production, in combination with fatty acid metabolism engineering via pah1Δ lpp1Δ dpp1Δ are1Δ and redox cofactor engineering via GPD deletion and GapN expressionBack to article page