Table 1 Previous attempts to optimize the medium or genetic background of Synechocystis sp. PCC 6803 for the production of PHB. Further approaches (also in other cyanobacteria) have been reviewed recently [19]
Genotype | PHB content (% CW) | substrate | Production condition | Polymer composition | References |
|---|---|---|---|---|---|
WT | 29 | 0.4% acetate | –P | PHB | [38] |
overexpression phaAB (native) | 35 | 0.4% acetate | –N | PHB | |
overexpression phaABC (Cupriavidus necator) | 11 | 10 mM acetate | –N | PHB | [42] |
overexpression nphT7, phaB, phaC | 41 | 0.4% acetate | Limited air exchange, –N | – | [28] |
overexpression Xfpk | 12 | CO2 | –N, –P | PHB | [5] |
overexpression sigE | 1.4 | CO2 | –N | PHB | [36] |
overexpression rre37 | 1.2 | CO2 | –N | PHB | [37] |