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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Metabolite secretions of Lactobacillus plantarum YYC-3 may inhibit colon cancer cell metastasis by suppressing the VEGF-MMP2/9 signaling pathway

Fig. 3

Relative gene expression of metastasis-related genes in colon cancer cells treated with Lactobacillus CFS. a Gene expression in Caco-2 cells; b Gene expression in HT-29 cells. Real-time PCR was carried out to assess changes in MMP2, MMP9, and VEGFA gene expression in colon cancer cells treated with Lactobacillus CFS (untreated group is the negative control and the 5-FU treatment group is the positive control; error bars represent mean of each group ± SD of three independent experiments; a–d, e–g, A–C, different letters in bars mean P < 0.05 (significant differences) by One-way ANOVA in the same group)

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Microbial Cell Factories

ISSN: 1475-2859

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