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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Metabolite secretions of Lactobacillus plantarum YYC-3 may inhibit colon cancer cell metastasis by suppressing the VEGF-MMP2/9 signaling pathway

Fig. 1

Lactobacillus CFSs inhibit Transwell™ invasion and migration of colon cancer cells. a The images of cell invasion in Caco-2 and HT-29. b Cell invasion of Caco-2; c Cell invasion of HT-29; d Cell migration of Caco-2; e Cell migration of HT-29. All CFS treatments inhibited Transwell invasion and migration compared with negative controls at the concentration of 80 μL/mL (untreated group is the negative control and the 5-FU treatment group is the positive control; error bars represent mean of each group ± SD of three independent experiments; a–d different letters in bars mean P < 0.05 (significant differences) by One-way ANOVA in the same group)

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