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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Differential role of segments of α-mating factor secretion signal in Pichia pastoris towards granulocyte colony-stimulating factor emerging from a wild type or codon optimized copy of the gene

Fig. 1

Schematic representation of truncations in the α-MAT secretory signal. a α-MAT consisting of the pre-region (19 amino acids), followed by a pro-region (66 amino acids) with three N-linked glycosylation sites (red box). Truncations, executed in the present study, in the pro-region of the α-MAT are shown. The position of the mutations is indicated by amino acid numbers b Schematic representation of the wild type and the truncated α-MAT (Δ57–70, shown as an example here) fused with the WT-GCSF. c Schematic representation of the wild type and the truncated α-MAT (Δ57–70, shown as an example here) fused with the CO-GCSF

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Microbial Cell Factories

ISSN: 1475-2859

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