Skip to main content
Fig. 8 | Microbial Cell Factories

Fig. 8

From: Immunogenicity evaluation of recombinant Lactobacillus casei W56 expressing bovine viral diarrhea virus E2 protein in conjunction with cholera toxin B subunit as an adjuvant

Fig. 8

On day 42 post-primary vaccination: a antigen-specific IgA-secreting cells in the intestinal Peyer’s patches of the mice in each group detected by IHC assay; b the splenocytes obtained from the mice in each group stimulated by E2 protein, followed by lymphocyte proliferation determination by MTT assay; c the levels of cytokines IL-2, IL-4, IL-10, IL-12, IL-17, and IFN-γ in serum samples collected from the mice in each group determined by ELISA; d the percentage of CD4+ and CD8+ T cells in the spleen lymphocytes of the mice in each group determined by flow cytometric analysis (d). The letters (a vs. b, b vs. c, c vs. d) indicate significant differences (p < 0.05); the letters (a vs. c, b vs. d) indicate significant differences (p < 0.01); the letters (a vs. d) indicate significant differences (p < 0.001)

Back to article page

Microbial Cell Factories

ISSN: 1475-2859

Contact us