Table 3 List of engineered strains of DSM 7029 used in this study

Redox gene overexpression

H7029-1

Epothilone C/D high-yield strain

This study

H7029-2

H7029-1-epoK

This study

H7029-3

H7029-1-epoK-fdx_0135

This study

H7029-4

H7029-1-epoK-fdx_2170

This study

H7029-5

H7029-1-epoK-fdx_2730

This study

H7029-6

H7029-1-epoK-fdx_4560

This study

H7029-7

H7029-1-epoK-fdx_5185

This study

H7029-8

H7029-1-epoK-fdx_6105

This study

H7029-9

H7029-1-epoK-fdx_S4580

This study

H7029-10

H7029-1-epoK-fdx_A6445

This study

H7029-11

H7029-1-epoK-fdr_0130

This study

H7029-12

H7029-1-epoK-fdr_7100

This study

H7029-13

H7029-1-epoK-fdr_S2240

This study

H7029-14

H7029-1-epoK-fdx_0135-fdr_0130

This study

H7029-15

H7029-1-epoK-fdx_0135-fdr_7100

This study

H7029-16

H7029-1-epoK-fdx_S4580-fdr_S2240

This study

Whole-cell biotransformation

7029-1

DSM 7029 derivate, harbouring pEOK101,

DSM 7029-empty vector

This study

7029-2

DSM 7029 derivate, harbouring pEOK102,

DSM 7029-epoK

This study

7029-3

DSM 7029 derivate, harbouring pEOK10,

DSM 7029-epoK-fdx_0135

This study

7029-4

DSM 7029 derivate, harbouring pEOK109,

DSM 7029-epoK-fdx_S4580

This study

7029-5

DSM 7029 derivate, harbouring pEOK11,

DSM 7029-epoK-fdr_0130

This study

7029-6

DSM 7029 derivate, harbouring pEOK112,

DSM 7029-epoK-fdr_7100

This study

7029-7

DSM 7029 derivate, harbouring pEOK113,

DSM 7029-epoK-fdr_S2240

This study

7029-8

DSM 7029 derivate, harbouring pEOK114,

DSM 7029-epoK-fdx_0135-fdr_0130

This study

7029-9

DSM 7029 derivate, harbouring pEOK115,

DSM 7029-epoK-fdx_0135-fdr_7100

This study

7029-10

DSM 7029 derivate, harbouring pEOK116,

DSM 7029-epoK-fdx_S4580-fdr_S2240

This study

Redox gene knock-out

JH01

H7029-14 derivate, fdx_0135 knock-out

This study

JH02

H7029-14 derivate, fdr_0130 knock-out

This study

JH03

H7029-12 derivate, fdr_7100 knock-out

This study