Skip to main content

Table 1 Comparison of BDO production using whey/lactose as substrate by different microorganisms

From: Efficient 2,3-butanediol production from whey powder using metabolically engineered Klebsiella oxytoca

Strain Substrate Method Concentration (g/L) Yield (g/g) Productivity (g/L/h) References
Bacillus polymyxa ATCC 1232 Cheese whey Wild-type 5.5 0.25 0.03 [22]
K. pneumoniae NCIB 8017 Rennet whey permeate Wild-type 7.5 0.46 0.08 [42]
K. oxytoca NRRL-13-199 Whey Wild-type, adding 50 mM acetate 8.4 0.365 [30]
Enterobacter aerogenes 3889 Whey Wild-type, using neutralized acid whey with 50 mM acetate 15.1 0.24 [23]
K. pneumoniae ATCC 13882 Whey Wild-type, using unsterilized acid whey and adjusting pH to 6.5 19.3 0.32 [23]
Lactococcus lactis mL001 Residual whey permeate (lactose) Deletion of ldh, ldhB, ldhX, pta, adhE, butBA, overexpression of bdh and lactose utilizing pathway in L. lactis MG1363 51 0.47 1.46 [32]
K. oxytoca PDL-K5 Whey powder Deletion of pox, pta, frdA, ldhD, pflB in K. oxytoca PDL-0 65.5 0.44 2.73 This study
K. pneumoniae KG1 Lactose Wild-type 4.38 0.33 0.365 [21]
K. oxytoca NRRL-B199 with nonviable cells of Kluyveromyces lactis CBS 683 Lactose Wild-type, co-immobilization by adhesion of β-galactosidase in nonviable cells of K. lactis with K. oxytoca 14.3 0.29 0.80 [25]
K. oxytoca ATCC 8724 Lactose Wild-type 32.49 0.207 0.861 [31]
K. oxytoca PDL-K5 Lactose Deletion of pox, pta, frdA, ldhD, pflB in K. oxytoca PDL-0 74.9 0.43 2.27 This study