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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Efficient 2,3-butanediol production from whey powder using metabolically engineered Klebsiella oxytoca

Fig. 1

Metabolic engineering strategies for efficient production of BDO from whey powder by K. oxytoca PDL-0. Solid lines represent one step reactions. Dashed lines represent multi-step reactions. Blue crosses indicated the blocked pathways in the metabolic engineered strain. The target product is shaded in red and the blocked byproducts are shaded in blue. G1P glucose-1-phosphate, G6P glucose-6-phosphate, LacY lactose permease, LacZ β-galactosidase, GlK glucose kinase, PGM phosphoglucomutase, PoxB pyruvate oxidase, PTA phosphotransacetylase, ACK acetate kinase, FrdA catalytic subunit of fumarate reductase, LdhD lactate dehydrogenase, PflB pyruvate formate-lyase, BudB α-acetolactate synthase, BudA α-acetolactate decarboxylase, BudC acetoin reductase

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